An area often overlooked during deployment of infrastructure applications is, exclusions from real-time scanning engines.

Below is the list of files and directories recommended for exclusion for SCSM (based on Forefront Protection)

Service Manager 2010 Files and Folders
%ProgramFiles%\Microsoft System Center\Service Manager 2010\Health Service State\*

Service Manager 2010 Processes
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%programfiles%\Microsoft System Center\Service Manager 2010\HealthService.exe
%programfiles%\Microsoft System Center\Service Manager 2010\Microsoft.Mom.ConfigServiceHost.exe
%programfiles%\Microsoft System Center\Service Manager 2010\MonitoringHost.exe
%programfiles%\Microsoft System Center\Service Manager 2010\Microsoft.Mom.Sdk.ServiceHost.exe